Alopecia universalis during treatment with leflunomide and adalimumab - Case report*
نویسندگان
چکیده
Alopecia areata is a non-scarring form of alopecia that can be localized or widespread. Its etiology is unknown, but immunological factors are implicated in its pathogenesis. With the more frequent use of anti TNFα biologic drugs, some alopecia areata cases during their use have been described. We report a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab and leflunomide.
منابع مشابه
Biologic agents and alopecia areata.
hibited hair growth and EGF, TNFand IL-1 completely abrogated it. All these evidences are in favor of an autoimmune phenomenon occurring in AA, with the TNFappearing as a potent inhibitor of hair growth. In the last few years, several biologic agents acting on TNFor involving ICAM 1-LFA1 or CD2-LFA3 interactions have been considered as possible treatments for AA. Cases of AA have been described...
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